Getting a prescription for tadalafil (the active ingredient in brand names Adcirca and Cialis) can be a more complicated experience than many men expect. While Cialis and its generic tadalafil are effective ED treatments, many men get overwhelmed by the dosages and ways to take the medication.
Like sildenafil (the active ingredient in Viagra), avanafil (sold as Stendra) and other ED medications, tadalafil is available in several dosages, but unlike the others, it can also be prescribed for daily use.
While the maximum dose of tadalafil for ED may give you intense arousal, it’s important to choose the right dosage for your individual needs to experience minimal side effects and avoid permanent or serious injury. Here’s what to know if you want the best results possible.
How Tadalafil Dosing Works
Since tadalafil is the longest-lasting medication for ED, you have to treat it differently than many other medications on the market. The key reason: A single dose of tadalafil may provide relief from ED for up to 36 hours — about one and a half days.
If we wade into the science for a moment, that means the half-life of tadalafil is approximately 17.5 hours. That’s a really long time — and it’s only an average. In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours.
As a long-lasting ED medication, tadalafil is only recommended for use one time per day. When used at a typical as-needed dosage, tadalafil remains effective for up to 36 hours.
For optimal results, it’s recommended to take tadalafil at least 30 minutes before you and your partner plan to have intercourse. But if you are intimate every four hours (high-five to that), you won’t want to use tadalafil every time — this could be very dangerous.
Tadalafil Dose Uses
Contrary to popular belief, tadalafil and other PDE5 inhibitors won’t make you get random arousal. Instead, proper use of tadalafil just increases blood flow to your member, meaning you’ll only get aroused when you receive stimulation.
Tadalafil works by inhibiting the effects of cGMP-specific phosphodiesterase type 5 (or PDE5) — an enzyme found in the smooth muscle cells of blood vessels. PDE5 plays a major role in regulating the flow of blood to certain parts of your body, including the arousal tissues of your member. By inhibiting the effects of PDE5, tadalafil makes it easier for blood to flow “downstairs” and for you to get hard.
This guide to PDE5 inhibitors has more information about how tadalafil, sildenafil and other medications for ED work. There are a number of common use cases for this medication, including:
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Daily tadalafil for ED
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On-demand tadalafil for ED
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Tadalafil for the symptoms of benign prostatic hyperplasia (BPH)
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Tadalafil for pulmonary arterial hypertension (PAH)
Let’s look at the actual dosages in more detail.
Tadalafil Dose and Timing Guide
The prescription drug is a PDE5 inhibitor, meaning it blocks phosphodiesterase type 5 enzymes that reduce blood flow to the penile tissues. So tadalafil essentially treats ED by increasing blood flow to your member, making it easier for you to get hard when you feel aroused.
Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours.
Tadalafil 10mg: Typical Starting Dose
10mg is the typical starting dosage of as-needed tadalafil. The medication is typically prescribed at this dosage for use as needed before intercourse for men with mild to moderate ED. And if you begin your ED treatment journey with tadalafil, you’ll almost certainly be prescribed a 10mg dose to start.
Research shows that most men with ED who use tadalafil at this dosage are able to have intercourse successfully. Still, it’s possible that this dosage won’t meet your individual needs. In this case, your healthcare provider may prescribe a higher dose. For all as-needed dosages, you’ll typically want to take tadalafil at least 30 minutes to two hours before you plan to get intimate.
Mild ED Dose: 5mg Tadalafil
If your ED is fairly mild, or if you develop side effects from using tadalafil at a higher dosage, your healthcare provider may prescribe tadalafil at a dosage of 5mg.
This is the lowest as-needed tadalafil dosage currently available. Although it’s slightly less effective than the 10mg and 20mg dosages at treating ED, it’s also less likely to cause certain side effects — which, for men with heart conditions and those vulnerable to dizziness, can be a necessary precaution for safe and effective use.
Tadalafil 20mg: Max Dose
If you don’t notice any improvements from a 10mg dosage, or don’t experience a big enough improvement to have satisfactory intercourse, your healthcare provider may prescribe a stronger 20mg dosage of tadalafil.
The maximum dosage of tadalafil is 20mg, used as needed for intercourse for men with more severe ED. If you’re prescribed tadalafil at this dosage, it’s likely because smaller doses weren’t giving you the results you were hoping for. Since tadalafil 20mg dosage is a higher dose, it’s important to follow your healthcare provider’s instructions and take your medication no more than once per day.
At this dosage, tadalafil is more effective at improving ED and helping men with ED have intercourse successfully. Research shows that a dosage of 20mg is particularly effective for men with severe ED. Clinical trials show that side effects from tadalafil are slightly more common at this dosage than at a lower dosage of 10mg, though the difference in tolerability is relatively small.
For Daily Tadalafil Dosing: 2.5mg and 5mg Tadalafil
While tadalafil is available as-needed, it’s also available for once-daily use in much smaller dosages for always-on preparedness for intimate activity. Daily dose tadalafil is available at a dosage of 2.5mg or 5mg tablets.
There might be several reasons to go with daily dosages instead of the dosages where you take the medication as needed. Using tadalafil daily offers several advantages, as explained in this full guide to daily-use Cialis.
However, keep in mind that daily use might change the side effect outcomes for some people. Side effects such as indigestion and flushing may become more frequent with daily use. When used daily, tadalafil should be taken at approximately the same time each day to maintain a stable concentration in the body.
Tadalafil Dosage Side Effects
It’s important to know that side effects can increase based on dosage, frequency of use and whether you’re on any other medications.
This comprehensive guide covers the numerous (and mostly tolerable) tadalafil side effects, but serious side effects at all dosages can include:
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Hearing loss
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Loss of vision
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Priapism (prolonged arousal without stimulation)
Once you and your healthcare provider work out the correct dosage for you, tadalafil should effectively improve your arousal and enhance your performance in the bedroom.
But there are also some potentially dangerous mistakes you’ll want to avoid when taking tadalafil — let’s look at those in the big picture of how to take the medication correctly.
Tadalafil Drug Interactions
Drug interactions can be serious business. If you’re taking certain medications, you might need a lower dose of tadalafil, so tell your healthcare provider if you use:
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Alpha blockers
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Nitrates, nitroglycerin and nitric oxide supplements
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Ketoconazole, itraconazole or other antifungal medications
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Tamsulosin
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Erythromycin
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Doxazosin
You should also tell your healthcare provider if you have renal or kidney disease, angina, Peyronie’s disease, an enlarged prostate or pulmonary hypertension (high blood pressure). You’ll want to avoid consuming grapefruit juice while taking tadalafil; the juice can lead to some of the same interactions as those of prescription drugs.
How to Take Tadalafil Dose for Best Results
Not following best practices around tadalafil can reduce the medication’s effectiveness, increase your risk of common side effects and generally make your tadalafil-taking experience less optimal. You don’t want to do any of those things intentionally. Instead, follow this guide. To get the best results from tadalafil, try to:
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Take tadalafil at least 30 minutes before intercourse. Tadalafil usually reaches its peak blood concentration between 30 minutes and six hours. If you’re prescribed tadalafil for use as needed, you’ll get the best results by taking it at least 30 minutes before you and your partner plan to be intimate. If you don’t notice any improvement, try taking tadalafil about two hours before intercourse.
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Limit your alcohol consumption. Taking tadalafil (Cialis) with alcohol may increase your risk of developing side effects, including reduced blood pressure. Alcohol can also affect your performance and ability to maintain arousal during intercourse. It’s okay to drink a small amount of alcohol while using tadalafil, but it’s best to avoid heavy drinking while using this medication.
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Combine tadalafil with a healthy lifestyle. Your cardiovascular health plays a key role in your ED and performance, meaning medications such as tadalafil work best if you live a healthy lifestyle.
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Avoid drug interactions. Medications and foods may cause problems with ED medication and intensify the effects of tadalafil. Beyond potential drug interactions, this also means that you shouldn’t double up on a missed dose.
Obviously, there are many things you can do to take tadalafil incorrectly, and the worst of them is, arguably, taking too much of the medication. For example, taking 40mg of tadalafil (two 20mg tablets) is not recommended when being used for ED. This dosage of tadalafil is higher than the typical recommended dose for ED and could increase your risk of developing side effects, including potentially harmful side effects.
Do not double your dose without professional supervision. And if you don’t experience improvements from tadalafil at a dosage of 10mg or 20mg, talk to your healthcare provider. They’ll be able to guide you through other steps so you can have a happy and healthy bedroom life.
Tadalafil Dosages for ED: Final Thoughts
If you’re one of the tens of millions of men in the United States affected by ED, medications like tadalafil can improve your arousal and make it easier to have satisfying intercourse.
But you have to take it properly and safely to get the results you want. The following cheat sheet will help you get what you need safely — and get your bedroom game back in action:
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Tadalafil is one of four FDA-approved oral medications for ED, along with sildenafil (Viagra), vardenafil (Levitra) and avanafil (Stendra).
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Tadalafil is a widely used medication, mostly prescribed to treat ED and sometimes to treat the symptoms of benign prostatic hyperplasia (BPH) as well as pulmonary arterial hypertension (under the brand name Adcirca).
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Compared to other ED medications, tadalafil is very long-lasting. On average, a typical 10mg dose of tadalafil can improve arousal function for up to 36 hours.
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Tadalafil is available in several dosages. As a treatment for ED, it’s typically prescribed at a dosage of 10mg for use as needed, which may be adjusted to 20mg or 5mg based on your response to the medication.
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For once-daily use, tadalafil is prescribed at a lower dosage of either 2.5mg or 5mg per day.
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As with other ED medications, there’s no “best” dosage of tadalafil for all. Your healthcare provider will work with you to choose the best dosage based on your desired health outcomes, including treatment for benign prostatic hyperplasia.
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You should be taking tadalafil or any ED medication only as directed with medical advice, which means no double-dosing without the approval of a healthcare professional.
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If medication isn’t helping, there’s more you can do. This guide to naturally protecting your arousal shares actionable, science-based tactics you can use to improve your intimacy health and get better results from tadalafil.
You can learn more about the treatment of ED and improving your performance in this guide to the most common ED treatments and drugs.
This article originally appeared on Hims.com and was syndicated by MediaFeed.org.
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Featured Image Credit: DepositPhotos.com.